Systems pharmacology

In addition to identifying individuals at high risk of disease and disease progression, we are interested in identifying drug targets and drug repurposing candidates to treat high-risk individuals. Using our multiomic data, we are able to utilize certain omics for risk stratification (e.g. genetics and transcriptomics) while using proteomics and metabolomics for drug repurposing analyses. Through collaborations with the Loscalzo, Manichetti, and Halu labs, we are leveraging state-of-the-art network medicine approaches to develop treatment approaches for high risk groups. We are building a multi-disciplinary systems pharmacology program utilizing multiple analytic approaches to translate Omics findings into actionable therapeutic strategies.